Top 10 Most Dangerous Spiders In The World

Normally spiders are not considered dangerous as their venom is not so toxic that can kill any human being, however their bites can result in severe pain and inflammation. Here is our list for top 10 most dangerous Spiders.

1. Brazilian Wandering Spider

Phoneutria_nigriventer

The Brazilian wandering spiders appear in Guinness World Records from 2010 as the world’s most venomous spider. Wandering spiders are so-called because they wander the jungle floor at night, rather than residing in a lair or maintaining a web. During the day they hide inside termite mounds, under fallen logs and rocks, and in banana plants (hence the “banana spider” nickname) and bromeliads. P. nigriventer is known to hide in dark and moist places in or near human dwellings.

Their venom contains a potent neurotoxin, known as PhTx3, which acts as a broad-spectrum calcium channel blocker that inhibits glutamate release, calcium uptake and also glutamate uptake in neural synapses. At deadly concentrations, this neurotoxin causes loss of muscle control and breathing problems, resulting in paralysis and eventual asphyxiation. In addition, the venom causes intense pain and inflammation following a bite due to an excitatory effect the venom has on the serotonin 5-receptors of sensory nerves. This sensory nerve stimulation causes a release of neuropeptides such as substance P which triggers inflammation and pain.

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